Currently supported platforms include Windows 95, 98, 2000, 2003, XP, Me, and NT 4.0. No service packs or other OS updates are required on any of the supported platforms.
I currently use and develop on Windows 2000 primarily, so Windows 2000 compatibility is foremost.
When new major features are introduced, I usually test them personally on all supported Windows versions.
The 16-bit version of Inno Setup was discontinued starting with version 1.3. Support for Windows NT 3.51 was discontinued starting with version 3.0.
Mau yang lebih lengkap silahkan kunjungi http://www.innosetup.com/isfaq.php#oscompat